The Prep SFC 50 from Sepiatec is a compact and easy-to-use chromatography system for preparative separations on analytical and semi-preparative columns by means of supercritical fluid chromatography (SFC).
The system offers the comprehensive benefits of SFC technology, such as faster separations, lower costs due to reduced consumption of organic solvents, as well as being more environmentally friendly at increased safety.
The Prep SFC 50 system is equipped with two 400 bar high-pressure pumps with 30 ml pump heads. The total flow – at a modifier portion of 40 % – is up to 50 ml/min. Chromatography columns with inner diameters ranging from 4 to 16 mm, and a length of up to 250 mm may be used.
The column oven for up to 6 columns, containing the chromatography columns together with the injection valve and the UV flow cell, is heatable up to 70 °C so that a uniform temperature is ensured. The Prep SFC 30 system is available with 9 gas-liquid-separators allowing a total of up to 8 fractio0ns + waste.
As fractions are collected in unpressurized state, not only is safety increased, but also handling is simplified, and limitations with respect to the size of fraction volumes do not exist. This option proves to be extremely convenient when working with stack injections.
As the dimensions of the Prep SFC 50 together with the integrated computer and 10” touch-screen amount to only 56 x 60 x 88 cm (W x D x H), this system requires a minimum of space in the laboratory. A separate computer or monitor is not necessary.
|Operating mode||1 analytical or semi-preparative column|
|Solvents||CO2 and organic solvents|
|Number of modifier solvents||1 standard, max. 4 solvents with optional selection valve|
|Total flow rates||Up to 50 ml/min at a modifier portion of 40 %|
|CO2 pump||30 ml pump head, 400 bar|
|Modifier pump||30 ml pump head, 400 bar|
|Operating pressure||Up to 300 bar, adjustable online backpressure control|
|Injection||Partial loop with syringe pump|
|Columns||4 to 16 mm ID, up to 250 mm length|
|Column oven||Ambient temperature up to 70 °C, 2 columns standard, 6 columns with optional valves|
|Detection||UV detector, wavelength 190 to 500 nm|
|Other detectors||DAD, ELSD, or mass spectrometer optional|
|Fraction collection||1 to 8 fractions, unlimited volumes, pressure free collection|
|Software||Prep SFC control software|
|System controller||Integrated PC, 15.6“ touch-screen, 16:9 format|
|Connections||3 USB ports, Ethernet, HDMI|
|Dimensions||56 x 60 x 88 cm (W x D x H)|
Specifications are subject to change without notice.