Sepiatec‘s new Prep SFC M5-250 system is a preparative system for separating chiral and achiral samples using supercritical fluid chromatography. The Prep SFC M5 system consists of the main module and the collector module. Both modules form a functional unit that can be configured in a variety of ways with different equipment.
Possibilities for collecting and processing fractions using the Prep SFC M5-50 system can be expanded with the optional sorter module. The sorter module is a handling robot designed for interacting with the collector module of the Prep SFC M5 system. It is available in a variety of different sizes and can be equipped with various gripper arms. A wide range of variants and functions is possible with the addition of various components:
The Prep SFC M5-250 system is controlled entirely by means of the Prep SFC control software which offers a clear menu structure enabling simple and intuitive operation. All input options are presented on just a few screens. The software includes a sequence editor for inputting separation parameters for different samples, functions such as stack injection with automatic suggestions for stack times and multiple options for fractionation. A computer at a separate work site can also be connected. If an optional mass spectrometer is used, control and data acquisition also take place directly via the Prep SFC control software.
Operating mode | 1 semi-preparative or preparative column |
Suitable columns | 15 to 30 mm ID, max. 250 mm in length |
Solvents | CO2 and organic solvents |
Number of modifier solvents | 1 standard, max. 4 with optional selection valve |
CO2 pump | 150 ml pump head, 400 bar |
Modifier pump | 150 ml pump head, 400 bar |
Add-on pump | 30 ml pump head, 400 bar (optional) |
Total flow rate, isocratic | 250 ml/ min at a modifier portion of 40% |
Total flow rate, gradient | 150 ml/ min |
Backpressure range | Up to 300 bar, adjustable online backpressure control |
Injection | Partial loop with syringe pump |
Column oven | Ambient temperature to 70° C, 10 columns |
UV Detector | Wavelength range 190 to 500 nm |
Other detectors | DAD, ELSD or mass spectrometer optional |
Fraction collector | Carousel collector: fraction volumes 10 to 500 ml, XY-collector: 72 vials 60 ml or 195 vials 10 ml, other fraction collectors available on request |
Software | Prep SFC control software |
System controller | Integrated PC, Windows, 15.6” TFT touch-screen |
Connections | 3 USB ports, Ethernet, HDMI |
Dimensions, weight | 91.5 x 60 x 88 cm (W x D x H), 148 kg |
Specifications subject to change without notice.
Technical data of the Prep SFC M5 sorter module available on request